16 ECTS credits
478 h study time

Offer 1 with catalog number 1018029BNR for all students in the 2nd semester at a (B) Bachelor - advanced level.

Semester
2nd semester
Enrollment based on exam contract
Impossible
Grading method
Grading (scale from 0 to 20)
Can retake in second session
Yes
Enrollment Requirements
Om een inschrijving te kunnen nemen voor 'fysiologie en pathofysiologie van orgaanstelsels' moet men ingeschreven of geslaagd zijn voor 'Anatomie van organen en embryologie' en voor 'Dissectie' EN moet men geslaagd zijn voor 'De cel: biomoleculen en metabolisme', 'De cel: structuur en functie', 'De cel: moleculaire biologie en signaaltransductie' en 'De cel: van cel tot weefsel'.
Taught in
Dutch
Faculty
Faculteit Geneeskunde en Farmacie
Department
Basis (bio-) medische wetensch
Educational team
Henri Schots
Hendrik Reynaert (course titular)
Danny Schoors
Robert Hilbrands
Marc Meysman
Activities and contact hours

126 contact hours Lecture
32 contact hours Seminar, Exercises or Practicals
30 contact hours Independent or External Form of Study
Course Content

Contents of the course

The lectures are divided in 7 parts : General and cell physiology, physiology and pathophysiology of cardiovascular, blood, respiratory, digestive, renal  and reproductive system.

We start with an introduction to physiology, general mechanisms and principles, homeostatic mechanisms including temperature regulation, physiology of membranes and body compartments, and muscle tissue (skeletal, heart and smooth). Furthermore, we discuss the cardiovascular system (Normal / pathology): Electrocardiography, atherosclerosis, ischemic heart disease, acute coronary syndromes, heart failure, mechanisms of cardiac arrhythmias, hypertension, and diseases of the pericardium. In the next part the blood as an organ is discussed including the composition of blood, production and normal functions of the RBC, WBC, platelets and clotting. Afterwards, we discuss several pathologies (anemia, leukemia, coagulation disorders). In the respiratory system we study the role of the respiratory system, components of the respiratory system, ventilation, diffusion, perfusion, respiratory mechanics of lungs and chest wall, breathing control, arterial blood gases, respiratory failure, obstructive lung disease, restrictive disease, vascular lung disease and pulmonary hypertension . In the next part, the full Gastrointestinal tract is discussed, including the mouth and salivary glands, esophagus, stomach, small and large intestine, exocrine pancreas and liver. The emphasis is on function and regulation mechanisms of motility, secretion and absorption. The pathological mechanisms that underlie disease are explained, among others motility, gastric ulcer, pancreatitis, liver fibrosis and cirrhosis, diarrhea, etc. In chapter on renal physiology, we discuss GFR, secretion and absorption, formation and concentration of urine, water and acid homeostasis, and mechanisms of renal disease. Finally, we discuss the physiology and pathophysiology of the reproductive system including sexuals differentiation, male and female reproductive systems, fertility, pregnancy, lactation.

Course material
Handbook (Recommended) : Hoffbrand's Essential Haematology, AV Hoffbrand and PAH Moss, 8de, Wiley-Blackwell, 9781119495901, 2019
Handbook (Recommended) : West's Pulmonary pathophysiology, The essentials, West - Luks, 9de, Wolters Kluwer, 9781496339447, 2017
Digital course material (Recommended) : Hand-outs, cursussen en beeldmateriaal, Canvas
Handbook (Recommended) : Medical Physiology, Walter F. Boron,Emile L. Boulpaep, 3de, Saunders, 9781455743773, 2016
Handbook (Recommended) : Pathophysiology of heart disease, A Collaborative Project of Medical Students and Faculty, Leonard S. Lilly, 7de, Lippincott Williams & Wilkins, 9781975152178, 2020
Handbook (Recommended) : West's Respiratory Physiology, The Essentials, West - Luks, 10de, Wolters Kluwer, 9781496310118, 2015
Additional info

For this course, several reference books are suggested.

Hand-outs, syllabi and slides will be provided on PointCarré.

Learning Outcomes

General Competences

Students who have completed the course, know the normal functioning of the human body (cells, tissues and organs). They know the functions of the various tissues and organs. They have knowledge and understanding of the integrated functioning of tissues and organs in the human body and the systems that underlie it. They know the mechanisms that form the basis of malfunctioning and can thus explain pathological situations. They can make connections between a deviation and the action that will be given by an organ / body.

They can apply this knowledge to explain and solve clinical problems.

Grading

The final grade is composed based on the following categories:
Oral Exam determines 100% of the final mark.

Within the Oral Exam category, the following assignments need to be completed:

  • Mondeling examen with a relative weight of 100 which comprises 100% of the final mark.

    Note: Mondeling examen

Additional info regarding evaluation

Evaluation

The exam is an oral exam. The examination covers the material taught during the lectures and  assesses the knowledge and understanding of the subject matter. The use of reference works is not allowed. Each part is questioned by the lecturer responsible for that part and / or by the coordinator of the course.

It may be that the examination is spread over more than one day.

The total point for the exam is the weighted average of the partial scores. The weight of each part depends on the number of course hours of each part. To obtain a credit, the total point (weighted average) must be ≥ 10/20. Moreover,  the score on each part must be ≥ 8/20. If the score on a part is <8/20, the final point is max 8/10 and thus no credit will be awarded. Absence from an exam component leads to a mark of 0 on this component. 

Before the final grade is disclosed, the lecturers will hold an internal deliberation, and they may deviate from these rules.

Partial exemption can be given for the 2nd session for parts with a score of ≥ 10/20 AND the total score (weighted average) for the exam was ≥ 12/20. The student who wishes to make use of this, sends an email to the lecturer, at the latest before the start of the 2nd session.

Scores are not transferable to the next year if no credit for the entire course was obtained.

The exam in the 2nd session is organized as in the 1st session.

Allowed unsatisfactory mark
The supplementary Teaching and Examination Regulations of your faculty stipulate whether an allowed unsatisfactory mark for this programme unit is permitted.

Academic context

This offer is part of the following study plans:
Bachelor of Medicine: Standard track (6 years) (only offered in Dutch)