3 ECTS credits
80 h study time

Offer 1 with catalog number 4009159FNR for all students in the 2nd semester at a (F) Master - specialised level.

Semester
2nd semester
Enrollment based on exam contract
Impossible
Grading method
Grading (scale from 0 to 20)
Can retake in second session
Yes
Enrollment Requirements
In order to enroll for this course, students must either simultaneously enroll for the course ‘Industrial micobiology’ or have successfully passed ‘Industrial micobiology’.
Taught in
Dutch
Faculty
Faculty of Sciences and Bioengineering Sciences
Department
Bio-Engineering Sciences
Educational team
Remy Loris (course titular)
Activities and contact hours
52 contact hours Seminar, Exercises or Practicals
Course Content

Introductory lecture (for all students together): by means of a comprehensive manual the practicals are explained in detail and the safety procedures are given (attendance obligatory). If the student is not present in the introductory lecture, the practicals can not be done..

Laboratory experiments (attendance obligatory):
1. Fermentation process with a bacteriocin-producing lactic acid bacterial strain: upstream processing, computer-controlled fermentation, and monitoring (on line and off line).

2. Fermentation process with a yeast strain: upstream processing, computer-controlled fermentation, and monitoring (on line and off line).
3. Analyses of the fermentation samples: determination of cell denisty (optical density and plating), cell dry mass (membrane filtration and gravimetry), antibacterial activity (bioassay), and residual sugars and organic acids and/or alcohols produced (HPLC).
3. Data processing (PC, Excel).
4. Modelling: build-up of a simple, mathematical model (PC, Excel).
5. Simulation excercise: first with a simple example, then with the experimentally collected fermentation data (PC, Excel).
6. Make-up of a report during the practicals (PC).

Course material
Course text (Required) : Geïntegreerd practicum industriële biotechnologie, Eigen syllabus
Additional info

Presence is mandatory

Learning Outcomes

General competencies

The autonomous performance (in group and under supervision) of the upstream processing, the follow-up of a bacterial fermentation and a yeast fermentation.
The generation of data concerning growth and product formation of a selected bacterial and yeast strain, and the processing, modelling, and simulation of these data.
 

Grading

The final grade is composed based on the following categories:
PRAC Lab Work determines 50% of the final mark.
PRAC Report determines 50% of the final mark.

Within the PRAC Lab Work category, the following assignments need to be completed:

  • WPO labowerk with a relative weight of 1 which comprises 50% of the final mark.

    Note: De beoordeling van het practicum is een gewogen gemiddelde van de inzet, de verantwoordelijkheidszin, de initiatiefname, de samenwerkingscapaciteit en de verslaggeving. Zowel groepsgebonden als individuele punten worden toegekend.

Within the PRAC Report category, the following assignments need to be completed:

  • WPO verslag with a relative weight of 1 which comprises 50% of the final mark.

    Note: De beoordeling van het practicum is een gewogen gemiddelde van de inzet, de verantwoordelijkheidszin, de initiatiefname, de samenwerkingscapaciteit en de verslaggeving. Zowel groepsgebonden als individuele punten worden toegekend.

Additional info regarding evaluation

The evaluation of the practicum is a weighted average of personal engagement, sense for responsability, sense for initiatives, cooperation capacity, and reporting. Both group-related and individual contribution to the evaluation.

Allowed unsatisfactory mark
The supplementary Teaching and Examination Regulations of your faculty stipulate whether an allowed unsatisfactory mark for this programme unit is permitted.

Academic context

This offer is part of the following study plans:
Master of Bioengineering Sciences: Cell and Gene Biotechnology: Medical Biotechnology (only offered in Dutch)
Master of Bioengineering Sciences: Cell and Gene Biotechnology: Agrobiotechnology (only offered in Dutch)
Master of Bioengineering Sciences: Cell and Gene Biotechnology: Synthetic Biotechnology (only offered in Dutch)
Master of Bioengineering Sciences: Chemistry and Bioprocess Technology: Food Biotechnology (only offered in Dutch)
Master of Bioengineering Sciences: Chemistry and Bioprocess Technology: Sustainable Chemical Biotechnology (only offered in Dutch)
Master of Bioengineering Sciences: Chemistry and Bioprocess Technology: Micro- and Nanobiotechnology (only offered in Dutch)