6 ECTS credits
150 u studietijd
Aanbieding 1 met studiegidsnummer 4012869ENR voor alle studenten in het 2e semester met een verdiepend master niveau.
During this class, we will study in detail several developmental operations.
We will use articles and analyze the published techniques, results and conclusions. Moreover, the chosen topics will show the importance of multi-disciplinary approaches when studying biological problems as well as illustrate new paradigms.
Such topics are for example:
* Establishment of a gradient of a morphogen
* Antero-posterior patterning in the mid/hindbrain boundary
* Establishment of a biological clock during somite formation
* Gene regulation leading to the formation of the limb
* From pancreas development to insulin secreting cells
Several PowerPoint presentation will be have to be made by each student group.
A new teaching approach is used for this class: the lectures transformed into a Virtual Laboratory.
The students will in groups of two analyze four scientific articles and one review paper on the same topic, from the same laboratory and published over a period of time. This allows to “see” the evolution of the science processes. Each group will receive each article in 2 parts, first the introduction, materiel & methods, figures and text of the results will be provided in advance and during the interactive class the discussion and perspective will be provided online.
This allows each group to propose working hypotheses, imagine the experimental approach, analyze the experiments and at the end to formulate their own discussion, conclusion and perspectives.
Afterwards they compare their hypotheses, interpretations and conclusions to those of the authors.
Based on: Hoskins SG, Stevens LM, Nehm RH. “Selective use of the primary literature transforms the classroom into a virtual laboratory” - Genetics. 2007 Jul;176(3):1381-9.
An active participation of the student is necessary and the presence during all the classes is MANDATORY.
One point of the final grade (on 20) will be substracted for each non-justified absence (justification based on the VUB/faculty rules).
A "blended learning" approach is used requiring the student to work in advance on his/her own and with the team mate. The study material (articles, video's, links, etc) will be provided beforehand online. The class period will be dedicated to discussion about the studied topics. It is recommended to bring a laptop/tablet in the class.
e-mail: luc.leyns@vub.be
Scientific articles will be made available online
This course unit has the following intended learning outcomes. At the end of the course unit, the student should be able to:
* know and understand the various developmental operation discussed in the course,
* analyze in depth experiments, the conclusions that can be made and the hypotheses that can be generated based on these results,
* propose experimental plan based on the knowledge acquired and,
* communicate orally to peers the scientific results as well as their own hypotheses.
The student will then know: how to tackle recent scientific paradigms in developmental biology , be able to autonomously analyze and report on a specific biological operation.
De beoordeling bestaat uit volgende opdrachtcategorieën:
Examen Mondeling bepaalt 100% van het eindcijfer
Binnen de categorie Examen Mondeling dient men volgende opdrachten af te werken:
During the oral exam, the student will present in 15 minutes a scientific topic (based on one or several scientific articles) under the form of a presentation. The article(s) will be provided several weeks in advance and focus on a topic similar to the one presented by the student.
Afterwards, this topic as well as the content of the course will be discussed (about 15 minutes) with the examiner.
Deze aanbieding maakt deel uit van de volgende studieplannen:
Master in de biomedische wetenschappen: management en bedrijfsleven
Master in de biomedische wetenschappen: klinische biomedische wetenschappen
Master in de biologie: onderwijs
Master of Biology: Molecular and Cellular Life sciences (enkel aangeboden in het Engels)
Master of Biomedical Research: Standaard traject (enkel aangeboden in het Engels)
Educatieve master in de wetenschappen en technologie: biologie (120 ECTS, Etterbeek)