Organic Chemistry: Reactivity

6 ECTS credits
155 h study time

Offer 1 with catalog number 1015282BNR for all students in the 2nd semester at a (B) Bachelor - advanced level.

Semester

2nd semester

Enrollment based on exam contract

Impossible

Grading method

Grading (scale from 0 to 20)

Can retake in second session

Yes

Enrollment Requirements

In order to enroll for this course, students must either simultaneously enroll for the course 'Organic Chemistry: Structural Aspects' or have successfully passed 'Organic Chemistry: Structural Aspects'.

Taught in

Dutch

Faculty

Faculty of Science and Bio-engineering Sciences

Department

Chemistry

Educational team

Steven Ballet (course titular)
Guido VERNIEST

Activities and contact hours

26 contact hours Lecture
39 contact hours Seminar, Exercises or Practicals

Course Content

Lectures

The next classes of compounds and types of reactions are being discussed:

Chapter 1: ORGANIC REACTIONS
Chapter 2: ALKYLHALIDES - NUCLEOPHILIC SUBSTITUTIONS
Chapter 3: ALKENES - ADDITIONS AND ELIMINATIONS
Chapter 4: ALKYNES
Chapter 5: AROMATIC COMPOUNDS - AROMATIC SUBSTITUTIONS
Chapter 6: ALDEHYDES and KETONEN I - NUCLEOPHILIC ADDITIONS
Chapter 7: AMINES
Chapter 8: CARBOXYLIC ACIDS AND DERIVATIVES - NUCLEOPHILIC ACYL SUBSTITUTION

Practical exercises:

Theoretical and two laboratory exercises (topics can vary). During the practicals, the basic principles of NMR, IR and MS analysis of small organic molecules is taught.

Course material

Course text (Required) : Organische Chemie: Reactiviteit, S. Ballet, VUB, 2220170007397, 2020
Handbook (Recommended) : Organic Chemistry, Clayden, Greeves, Warren and Wothers, 2de, Oxford University Press, 9780199270293, 2012
Handbook (Recommended) : Organic Chemistry, Solomons & Fryhle, 8th ed., Wiley, 9781119248972, 2017

Additional info

The practical sessions (26 hours) teach the students how to convert theory into practice. This is realized via the drawing of mechanisms and solving typical issues/problems in organic synthesis. These sessions are not compulsory.

The laboratory practicals (13 hours) consist of two sessions in which the students are introduced in practical organic synthesis. Prior to these two sessions, an introductory course on lab safety is given. The evaluation is continuous by the supervisor and counts for 10% in the final score. The lab sessions are, in contrast to the theoretical exercises, compulsory. If absent without legitimate grounds, the student will receive a zero mark for the lab session.

Examples of reactions performed include the synthesis of t-butylchloride and the nitration of bromobenzene.

Additional theoretical information can be found in:

ORGANIC CHEMISTRY, Clayden, Greeves, Warren and Wothers, Oxford University Press, 2001

of

ORGANIC CHEMISTRY, Solomons & Fryhle, 8th Ed. Wiley, 2004

Learning Outcomes

General competences

The major aim of the bachelor formation "introducing the student in the main fields of chemistry" is of application with regard to organic chemistry.

The students gain insight in and knowledge of the reactivity of organic compounds, via the discussion of the most important classes of compounds and their most important functional groups.

The learning outcomes are the understanding of the reactivity of organic compounds and insight in reaction mechanisms.

Grading

The final grade is composed based on the following categories:
Oral Exam determines 70% of the final mark.
Written Exam determines 20% of the final mark.
PRAC Lab Work determines 10% of the final mark.

Within the Oral Exam category, the following assignments need to be completed:

oral examination (theory) with a relative weight of 1 which comprises 70% of the final mark.

Note: oral exam with written preparation.

Within the Written Exam category, the following assignments need to be completed:

written exam (exercises) with a relative weight of 1 which comprises 20% of the final mark.

Within the PRAC Lab Work category, the following assignments need to be completed:

evaluation practical sessions with a relative weight of 1 which comprises 10% of the final mark.

Note: The evaluation is continuous during the practical sessions and counts for 10% of the final grade.

Additional info regarding evaluation

Oral examination with written preparation (70% of final grade) and written exam (20% of final grade)

During the oral discussion knowledge and insight are tested.

The evaluation of the practical laboratory sessions accounts for 10% of the final grade.

Allowed unsatisfactory mark

The supplementary Teaching and Examination Regulations of your faculty stipulate whether an allowed unsatisfactory mark for this programme unit is permitted.

Academic context