Biomedical Devices: Sensors, Stimulators and Drug Delivery Systems

4 ECTS credits
120 h study time

Offer 1 with catalog number 4021672FNR for all students in the 2nd semester at a (F) Master - specialised level.

Semester

2nd semester

Enrollment based on exam contract

Impossible

Grading method

Grading (scale from 0 to 20)

Can retake in second session

Yes

Taught in

English

Partnership Agreement

Under interuniversity agreement for degree program

Faculty

Faculteit Ingenieurswetenschappen

Department

Electronics and Informatics

External partners

Universiteit Gent

Educational team

Johan Stiens (course titular)
Eowyn Van Wittenberghe
Angel Sole Morillo
Bruno Tiago da Silva Gomes

Activities and contact hours

24 contact hours Lecture
18 contact hours Seminar, Exercises or Practicals
4 contact hours Independent or External Form of Study

Course Content

Position of the Course:

The aim of the course is to give an in-depth overview of biomedical devices covering a large variety of sensors, comprising on body measurement systems, on exoskeletons, wearable sensor technologies, implantable sensing and drug deliverable devices, stimulation devices and point of care diagnostics, including microfluidic based medical devices. The course will also bring insights in the basic building blocks and functionalities of body area networks.

Content:

1. Biomedical Sensors:

- Global overview and general architectures: electrical, optical, mechanical, fluids, molecular

- Wearables

- Point-of-care including microfluidic systems

2. Stimulation devices

- Electrodes and Optrodes

- Electrostimulation generators: current, voltage, charge including organic electronic ion pumps

- Amplifier circuits

3. Drug delivery implants

- Micro-needle systems

- MEMS based systems

o Passive vs. active micropumps

o Continual delivery monitoring

- Intravenous drug deliverable systems

4. Electronic and Peripheral Components for implantable devices

- Electrodes, optrodes and transducers

- Inner structure of implantable devices

- Body sensor and body area networks

Case studies related to Fluorescence lifetime imaging microscopy.

5. Microfluidic based devices and fabrication technologies

Course material

Digital course material (Required) :

Additional info

Keywords

Biomedical sensors, transducers, stimulation devices, drug delivery implants, diagnostics, interfacing, wearable technologies, implantable technologies and associated electronic components, communication systems, body area networks.

Conditions for credit contract

Access to this course unit via a credit contract is determined after successful competences assessment

Conditions for exam contract

This course unit cannot be taken via an exam contract

Teaching methods

Lecture, lecture: plenary exercises, seminar: PC exercises

Learning materials and price

Combined syllabus-powerpoint will be available.

References

· Scientific literature.

· Microfluidic Devices for Biomedical Applications, X. James Li & Y Zhou

· Implantable Medical Electronics, Vinod Kumar Khanna

· Medical Devices and human Engineering, J. D. Bronsino & D.R. Peterson

Initial competences:

• Broad insights in general physics

• Principles of physiological systems

• Principles of electromagnetism

• Principles of electronic circuits and devices

Learning Outcomes

Final Competences

• Understanding the physical operation principles of biomedical devices

• Quantification and transduction of sensor signal into relevant physical quantities

• Skills for the selection of operation parameters of stimulation devices

• Understanding the design constraints of the electronic and peripheral components of implantable devices

• Decision capabilities for selection of suitable micro-pump systems in implantable systems

• Design skills of multi-modal Body Area Networks

• Understanding microfluidic systems for point-of-care applications

• Having insight into microelectronics and microfluidics fabrication technologies for biomedical devices

Grading

The final grade is composed based on the following categories:
Oral Exam determines 75% of the final mark.
PRAC Practical Assignment determines 25% of the final mark.

Within the Oral Exam category, the following assignments need to be completed:

Closed+oral open book exam with a relative weight of 75 which comprises 75% of the final mark.

Note: During examination period: combination of closed and oral open book exam, written preparation.

Calculation of the examination mark: During examination period / Throughout semester = 75% / 25%

Within the PRAC Practical Assignment category, the following assignments need to be completed:

Practical Lab session with a relative weight of 25 which comprises 25% of the final mark.

Note: During semester: 1 practical laboratory session

Additional info regarding evaluation

Evaluation methods: End-of-term evaluation and continuous assessment

Examination methods in case of periodic evaluation during the first examination period: Combination of Closed and Open book examination, oral examination

Examination methods in case of periodic evaluation during the second examination period: Combination of Closed and Open book examination, oral examination

Examination methods in case of permanent evaluation: Report

Possibilities of retake in case of permanent evaluation: Examination during the second examination period is possible

Extra information on the examination methods: During examination period: combination of closed and oral open book exam, written preparation; During semester: 1 practical laboratory session

Calculation of the examination mark: During examination period / Throughout semester = 75% / 25%

Allowed unsatisfactory mark

The supplementary Teaching and Examination Regulations of your faculty stipulate whether an allowed unsatisfactory mark for this programme unit is permitted.

Academic context