9 ECTS credits
270 h study time

Offer 1 with catalog number 1023144BNR for all students in the 2nd semester at a (B) Bachelor - advanced level.

Semester
2nd semester
Enrollment based on exam contract
Impossible
Grading method
Grading (scale from 0 to 20)
Can retake in second session
Yes
Enrollment Requirements
Om een inschrijving te kunnen nemen voor 'Klinische farmacologie en farmacotherapie' moet men ingeschreven of geslaagd zijn voor 'Farmacologie en farmacokinetiek', 'Fysiologie van de cel en organen' en 'Farmaceutische microbiologie: theorie + practicum' voor de opleiding Farmaceutische Wetenschappen. Voor de Master Biomedische Wetenschappen én de Master Biomedical Research geldt : Om een inschrijving te kunnen nemen voor 'Klinische farmacologie en farmacotherapie' moet men ingeschreven of geslaagd zijn voor 'Farmacologie : basisconcepten' én voor 'Gebruik van diermodellen in de biomedische wetenschappen'.
Taught in
Dutch
Faculty
Faculteit Geneeskunde en Farmacie
Department
Pharmaceutical and Pharmacological Sciences
Educational team
Alain Dupont (course titular)
Patrick Lacor
Ilse Smolders
Souad Moudallel
Activities and contact hours

65 contact hours Lecture
10 contact hours Seminar, Exercises or Practicals
Course Content

During the first part of the course, the main classes of medicines are reviewed. For this purpose, the Gecommentarieerd Geneesmiddelen Repertorium is used, so that students at the same time learn how to use this source of information. This course emphasises the operational mechanisms of the main medicines, the main indications, counter-indications and side-effects, the main pharmacokinetic aspects for clinical practice, clinically relevant interactions with other medicines and the precautions to be taken in clinical practice.

The second part of the course covers "general" aspects of pharmacotherapy. They include:
- rational and evidence-based pharmacotherapy
- the practical approach to pharmacotherapeutic problems
- elementary notions of how medicines are discovered, developed and registered
- a good understanding of how medicines are evaluated (including clinical study designs, randomised controlled studies, observational studies, pharmacoepidemiology, pharmacoeconomy)
- knowledge of how medicines are to be prescribed and how this is regulated
- pharmacotherapy for special patient groups (elderly people, children, pregnancy, breastfeeding, kidney insufficiency, liver insufficiency, heart failure, etc.)
- pharmacotherapy and genetic polymorphism
- therapy loyalty
- detection and classification of side-effects, causal relations, post-marketing drug surveillance

The Seminars, Exercises and Practicals cover various pharmacotherapeutic problems which GPs are frequently confronted with.

Course material
Digital course material (Required) : Cursusnota's en kopies van de gebruite overheads; Gecommentarieerd Geneesmiddelen Repertorium; Folia Farmacotherapeutica, Canvas
Handbook (Recommended) : Algemene Farmacotherapie, Van Ree, 2de druk, Bohn Stafleu Van Loghum, 9789035228665, 2006
Handbook (Recommended) : Stahl's Essential Psychopharmacology, Neuroscientific basis and practical applications, Stephen M Stahl, 4de, Cambridge University Press, 9781107686465, 2013
Handbook (Recommended) : Pharmacology, Rang, Dale, Ritter, Moore, 9de, Churchill Livingstone, 9780702074486, 2019
Digital course material (Required) : Website van het Belgisch Centrum voor Farmacotherapeutische Informatie: http://www.bcfi.be, http://www.bcfi.be
Additional info

All material is uploaded via the e-learning platform.

Gecommentarieerd Geneesmiddelen Repertorium; Folia Farmacotherapeutica
Website of the Belgisch Centrum voor Farmacotherapeutische Informatie: http://www.bcfi.be

Complementary study material:
Pharmacology, Rang, Dale, Ritter, Moore, Churchill Livingstone, 2003 

Stahl's Essential Psychopharmacology: Neuroscientific basis and practical applications, Stephen M Stahl, Cambridge University Press, 2008 

Learning Outcomes

General competencies

Students should acquire an understanding of the operational mechanisms, the favourable and adverse pharmacological effects and the other clinically relevant effects (pharmacokinetics, interactions) of the main classes of medicines.
Students will learn how to obtain information about medicines, how to critically assess this information and which criteria can be used for selecting medicines and composing a personal formulary.
Student will also acquire an understanding of the basic concepts of rational pharmacotherapy and learn how to use the right medicine in the right way.

Grading

The final grade is composed based on the following categories:
Written Exam determines 100% of the final mark.

Within the Written Exam category, the following assignments need to be completed:

  • Schriftelijk examen with a relative weight of 1 which comprises 100% of the final mark.

    Note: Schriftelijk examen

Additional info regarding evaluation

Written examination with mainly open questions, some multiple choice questions are possible.

The final exam score is calculated a following: 60% for part I (Prof Dupont), 30% for part II (Prof Smolders), 10% for part III (Prof Lacor). When a student obtains a score of less than or equal to 7/20 for one of the 3 parts, this score will count as the final exam score.   

Because multiple correct answers are possible for the multiple choice examination, the 'giscorrectie' will not be applied.

Allowed unsatisfactory mark
The supplementary Teaching and Examination Regulations of your faculty stipulate whether an allowed unsatisfactory mark for this programme unit is permitted.

Academic context

This offer is part of the following study plans:
Bachelor of Pharmaceutical Sciences: default (only offered in Dutch)
Bachelor of Pharmaceutical Sciences: Verkort traject (only offered in Dutch)
Master of Biomedical Sciences: Management and Business (only offered in Dutch)
Master of Biomedical Sciences: Clinical Biomedical Sciences (only offered in Dutch)
Master of Biomedical Research: Standaard traject